MW 451.6 Da, Purity >96%. Potent, non-selective HDAC inhibitor (IC₅₀ values are 14, 20, 26 and 75 nM for HDAC6, 1, 4, and 3, respectively and 2 μM for HDAC2). Antiproliferative agent. Induces oxidative stress and oxidative DNA damage. Shows antitumor effects in vivo. Orally active.
The product is subject to the following: Abcam Restricted Use Statement